43 year old female with Pedal Edema, Generalised Weakness.

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I have been given this case to solve in an attempt to understand the topic of " patient clinical data analysis" to develop my competency in reading and comprehending clinical data including history, clinical findings, investigations and come up with diagnosis and treatment plan.





 43 year old female resident of Narketpally came to OPD with chief complaints of  

Swelling in bilateral lower limbs upto ankle since 15 days 

Generalised weakness since 1 week 


HISTORY OF PRESENTING ILLNESS: 

Patient was apparently asymptomatic 15 days ago. She noticed swelling in her both lower limbs until ankle , insidious in onset , gradually progressive in nature , Pitting type . No aggravating and relieving factors.

H/o generalised weakness since 1 week.

Increased menstrual bleeding since 3 months but duration remained same not associated with clots .

No h/o orthopnea and paroxysmal nocturnal dyspnea.

No h/o decreased urine output, burning micturition .

No H/o nocturia, polyuria 

No H/o nausea, vomiting, loose stools, constipation.

No H/o fever, cough ,cold .

No H/o palpitations, sweating .

No H/O chest pain.

No H/o abdominal distension, abdominal pain.

No H/o hematuria.

No h/o headache,sleep disturbances.


PAST HISTORY: 

4 years ago , patient had complaints of generalised weakness and visited her local doctor , blood investigations were done and her Hemoglobin was around 6 gm/dl .

So she took iron and folic acid supplements for a month and stopped. 

On 19 Jan 2024 , patient came with similar complaints to our OPD , investigations like complete blood picture,serum electrolytes , creatinine and blood urea were done and was advised to get admitted .

Not a k/c/o Diabetes Mellitus, Hypertension, Tuberculosis,CAD, Thyroid disorders.

MENSTRUAL HISTORY: 

Menarche - 13 years 

28/5 - regular periods 

Earlier 2- 3  pads / day 

Not associated with clots . 

Since  3  months increased bleeding during periods , duration remained same 

Pads / day  - 4 pads / day ( wholly filled)


PERSONAL HISTORY: 

Diet - mixed  

Sleep - Adequate 

Appetite - normal

Bowel and bladder - regular

No addictions

No allergies  

FAMILY HISTORY: 

No significant history  


GENERAL EXAMINATION: 

Patient is conscious, coherent and co-operative.

She is moderately built and moderately nourished.

Pallor - Present  



Icterus - Absent

Cyanosis - Absent 

Clubbing - Absent 

No lymphadenopathy

On examination,edema is present below knee level


    

 



Vitals : 

Temperature - 96.8 ° F

Blood Pressure -110/70 mmHg

Pulse Rate -89 bpm

Respiratory Rate - 16 cpm

SYSTEMIC EXAMINATION: 


Per abdomen:- 

On inspection

Shape of abdomen : flat

Umbilicus : inverted 

Movements of abdomen wall with respiration 

No visible peristalsis, pulsations, sinuses, engorged veins, hernial sites 

On palpation 

No local rise of temperature 

Inspectors findings are confirmed 

Soft and non tender

No palpable mass 

Liver is not palpable 

Spleen is not palpable 

On percussion 

Resonance note heard

On auscultation 

Bowel sounds heard  








CVS Examination: 

Inspection

No raised JVP 

Trachea appears to be central 

The chest wall is bilaterally symmetrical

No dilated veins, scars or sinuses are seen

Palpation- 

Trachea Central in position 

Apex beat is felt in the fifth intercostal space, 1 cm medial to the midclavicular line

Auscultation-

S1 and S2 heard, no  murmurs  heard 


Respiratory Examination: 

Shape of chest is elliptical, b/l symmetrical.

Trachea is central. Expansion of chest is symmetrical

 Bilateral Airway Entry - positive

 Normal vesicular breath sounds 


CNS Examination: 

Conscious

Normal speech.

No neurological deficit found.


PROVISIONAL DIAGNOSIS: 

Anemia under evaluation 

Nutritional? Menstrual blood loss? 


INVESTIGATIONS:  

On 19 Jan 2024 .

Complete Blood picture:-



Serum electrolytes 


 


Serum creatinine


Blood urea 


Complete Urine Examination


USG report  


Positive findings - borderline splenomegaly 

Right renal calculi 

ECG 

Heart rate -100 bpm ( tachycardia) 

Normal sinus rhythm 

Normal axis



On 23 Jan 2024

Hb- 5gm/dl 

TLC - 5800 

MCV - 61.7 

MCHC - 23.1

MCH - 14.3 

Platelet - 3.0  

Serum iron - 31 micro gram / dl 

Blood urea - 22 mg/dl 

Serum creatinine - 0.6 mg/ dl 

Blood grouping - B +ve 

Serum ferritin - 


Liver function tests : 



Chest x-ray



On 24 Jan 2024

Fasting Blood sugar -285 mg/dl  

FINAL DIAGNOSIS: 

Severe Anemia Nutritional? Menorrhagia?

Denovo Diabetes mellitus 



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